What is the aspirin dose and route for suspected cardiac origin?

What is the aspirin dose and route for suspected cardiac origin?

• A. 325 mg chewable PO (up to 325 mg)
• B. 324 mg chewable PO (up to 325 mg)
• C. 162 mg chewable PO
• D. 325 mg transdermal

Answer: (B)

When aspirin is given for a suspected cardiac event, the goal is to rapidly inhibit platelet aggregation with an oral, chewable dose in the range commonly used for ACS. The best choice is about 324 mg by mouth, up to a maximum of 325 mg. This typically means four 81 mg chewables, which provides a rapid, effective dose without exceeding the usual limit. The other options don’t fit as well. A single 325 mg chewable is not a common available form, and 162 mg is lower than the typical ACS dose. A transdermal route isn’t used for aspirin in this scenario.

When aspirin is given for a suspected cardiac event, the goal is to rapidly inhibit platelet aggregation with an oral, chewable dose in the range commonly used for ACS. The best choice is about 324 mg by mouth, up to a maximum of 325 mg. This typically means four 81 mg chewables, which provides a rapid, effective dose without exceeding the usual limit.

The other options don’t fit as well. A single 325 mg chewable is not a common available form, and 162 mg is lower than the typical ACS dose. A transdermal route isn’t used for aspirin in this scenario.